Outcome switching is a major problem in clinical trial reporting that distorts the evidence doctors and patients use to make real-world clinical decisions. Numerous prevalence studies have already shown this to be an extremely common problem, even in top medical journals. However the CEBM Outcome Monitoring Project (COMPare) has taken a new approach: writing to journals to correct the record on individual trials, in the hope that individual accountability and open data sharing will help solve this important problem. Our main question was: how will the journals respond? This blog tells the story of COMPare so far.
Join S4BE at the International Student EBM Congress on Kish Island in December 2015!
Iván Murrieta Álvarez takes an in depth look at determining the probability that a patient has a certain illness, using only a pen and paper.
The relationship between Shared Decision Making and EBM; two separate disciplines or not? Read Ammar’s piece on this subject and have your say.
Surrogate endpoints are like a double edged sword. Even though they do have some benefits on some occasions, they can easily mislead doctors into withdrawing the wrong conclusions. It is, therefore, important to use them with caution.
Have you been asked to present some slides on an evidence-based topic? This blog can help!
If you are new to EBM and methods such as critical appraisal, it can be daunting, but the CEBM tools are a useful introduction for beginners.
Whether you couldn’t get enough of the rolling coverage of the royal birth, or couldn’t wait for it to be over, I have here for you a roundup of some of the recent systematic reviews and evidence related to pregnancy and childbirth (royal or otherwise).
There’s a lot of evidence out there of varying quality. This slideshow looks at the uses of grading medical evidence, and how it can be done.
This slideshow shows how the data generated in trials and analysed in systematic reviews can be applied in clinical practice.
What is the future of EBM in the US, both in policy and in reality?
Your patient has mild hypertension. What should you do?
Treat the hypertension.
Okay, how should you treat the hypertension?
Well, let’s start with HCTZ, that’s well-tolerated.
What will that do?
It’s a diuretic; it’ll help her get rid of the extra volume.
Okay, what will that do?
It’ll lower her blood pressure.
Okay, what will that do?
What do you mean, what will that do?
What will lowering her blood pressure do?
It’ll lower her blood pressure! Seriously—who are you anyway?
The NHS Evidence website provides a great starting block for many clinical questions, gathering information from several NHS websites as well as several journals.